Asian consensus on irritable bowel syndrome

วันที่ 10 กรกฎาคม 2563      

SPECIAL ARTICLEjgh_6353 1189..1205

Asian consensus on irritable bowel syndrome

Kok-Ann Gwee,1 Young-Tae Bak,2 Uday Chand Ghoshal,3 Sutep Gonlachanvit,4 Oh Young Lee,5

Kwong Ming Fock,6 Andrew Seng Boon Chua,7 Ching-Liang Lu,8 Khean-Lee Goh,9

Chomsri Kositchaiwat,10 Govind Makharia,11 Hyo-Jin Park,12 Full-Young Chang,13 Shin Fukudo,14

Myung-Gyu Choi,15 Shobna Bhatia,16 Meiyun Ke,17 Xiaohua Hou18 and Michio Hongo19

1Stomach Liver and Bowel Clinic, Gleneagles Hospital, Singapore; 2Department of Internal Medicine, Korea University College of Medicine, Seoul,

South Korea; 3Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India; 4Department of

Internal Medicine, Chulalongkorn University, Bangkok, Thailand; 5Department of Gastroenterology, College of Medicine, Hanyang University,

Seoul, South Korea; 6Division of Gastroenterology, Changi General Hospital, Singapore; 7Ipoh Gastro Centre, Ipoh, Malaysia; 8Division of

Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan; 9Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia;

10Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 11Department of Gastroenterology and Human Nutrition, All India Institute of

Medical Sciences, New Delhi, India; 12Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea; 13Division of

Gastroenterology, Taipei Veterans General Hospital, and National Yang-Ming University School of Medicine, Taipei, Taiwan; 14Department of

Behavioral Medicine, Tohoku University Graduate School of Medicine, Aoba Sendai, Japan; 15Seoul St Mary’s Hospital, The Catholic University of

Korea, Seoul, South Korea; 16Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Parel, Mumbai, India;

17Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical

College, Beijing, 18Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; and 19Department of

Comprehensive Medicine, Tohoku University Hospital, Aoba Sendai, Japan


Background and Aims: Many of the ideas on irritable bowel syndrome (IBS) are derived

from studies conducted inWestern societies. Their relevance to Asian societies has not been

critically examined. Our objectives were to bring to attention important data from Asian

studies, articulate the experience and views of our Asian experts, and provide a relevant

guide on this poorly understood condition for doctors and scientists working in Asia.

Methods: A multinational group of physicians from Asia with special interest in IBS

raised statements on IBS pertaining to symptoms, diagnosis, epidemiology, infection,

pathophysiology, motility, management, and diet. A modified Delphi approach was

employed to present and grade the quality of evidence, and determine the level of


Results: We observed that bloating and symptoms associated with meals were prominent

complaints among our IBS patients. In the majority of our countries, we did not observe a

female predominance. In someAsian populations, the intestinal transit times in healthy and

IBS patients appear to be faster than those reported in the West. High consultation rates

were observed, particularly in the more affluent countries. There was only weak evidence

to support the perception that psychological distress determines health-care seeking.

Dietary factors, in particular, chili consumption and the high prevalence of lactose malabsorption,

were perceived to be aggravating factors, but the evidence was weak.

Conclusions: This detailed compilation of studies from different parts of Asia, draws

attention to Asian patients’ experiences of IBS.

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